Vutiglabridin, CAS [[1800188-47-9]]

Product Overview

• Article Name: Vutiglabridin, CAS [[1800188-47-9]]
• Biozol Catalog Number: TGM-T61268
• Supplier Catalog Number: T61268
• Alternative Catalog Number: TGM-T61268-1MLX10MM(INDMSO),TGM-T61268-1MG,TGM-T61268-5MG,TGM-T61268-10MG,TGM-T61268-25MG,TGM-T61268-50MG,TGM-T61268-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: HSG4112

Product Description

Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stability. vutiglabridin ameliorates mptp-induced neurodegeneration in Parkinsons disease mice by targeting mitochondrial paraoxonase-2. Vutiglabridin is a clinical phase 2 drug for the treatment of obesity and has therapeutic effects on p-mitochondrial PON2 in a PD model. vutiglabridin penetrates the brain, binds PON2, and restores 1-methyl-4-phenylpyridine (MPP*)-induced neuroblastoma in SH-SY5Y Vutiglabridin significantly attenuated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dyskinesia and dopaminergic neuronal damage in mice modeled with PD in mouse experiments.

Product Properties

• Molecular Weight: 354.44
• Purity: 99.07%
• CAS Number: [1800188-47-9]
• Formula: C22H26O4
• Target: ROS|||Phosphatase|||Others|||PPAR|||Antibacterial

Images

T61268