GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
Molecular Weight:
507.63
Purity:
99.73%
CAS Number:
[942918-07-2]
Formula:
C30H33N7O
Target:
Aurora Kinase|||AMPK|||FLT|||Apoptosis|||Tie-2
T6129
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