NTPDase-IN-1 (compound 5a) is a selective inhibitor of NTPDase enzymes with IC50 values of 0.05 µM, 0.23 µM, and 0.54 µM against h-NTPDase-1, h-NTPDase-2, and h-NTPDase-8, respectively. It exerts non-competitive inhibition on h-NTPDase-1 and h-NTPDase-2, with a Km value of 21 µM for h-NTPDase-1. This compound is useful for investigating conditions such as cancer, immunologic disorders, and bacterial infections [1].
Molecular Weight:
363.54
Formula:
C18H25N3OS2
Target:
Others|||Phosphatase
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