IDO1/TDO-IN-1 (30) is a highly effective inhibitor of IDO1 and TDO enzymes, acting through uncompetitive (Ki = 0.23 µM) and competitive (Ki = 0.73 µM) mechanisms, respectively. This compound exhibits significant capacity to induce cell apoptosis via the potential mitochondria-mediated Bcl-2/Bax pathway [1].
Molecular Weight:
364.35
CAS Number:
[2379527-72-5]
Formula:
C21H16O6
Target:
Others|||IDO|||Apoptosis|||Indoleamine 2,3-Dioxygenase (IDO)|||Bcl-2 Family
T61385
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