NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1beta release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
Molecular Weight:
365.19
Purity:
99.63%
CAS Number:
[2641826-39-1]
Formula:
C17H14BrFO3
Target:
NOD-like Receptor (NLR)|||NOD
T61392
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