TRPC3/6-IN-1 is a highly potent and selective inhibitor that blocks the activity of canonical transient receptor channels TRPC3 and TRPC6, showing significant potency against human isoforms hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. This compound is valuable for research on chronic models of heart failure [1].
Molecular Weight:
365.45
CAS Number:
[736945-96-3]
Formula:
C20H19N3O2S
Target:
TRP/TRPV Channel|||Others
T61407
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