TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, exhibiting an IC50 of 2.14 µM for NO production inhibition. It demonstrates anti-inflammatory properties by inhibiting downstream protein phosphorylation and preventing TOPK degradation [1].
Molecular Weight:
368.31
CAS Number:
[2745108-35-2]
Formula:
C17H15F3N2O4
Target:
JNK|||Others
T61440
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