HIF-1/2alpha-IN-1, an orally active compound, functions as an inhibitor of HIF-2alpha. Its inhibitory effect on HIF-2alpha activity is significant, with an IC 50 value of 0.92 µM. Furthermore, HIF-1/2alpha-IN-1 has the ability to decrease HIF-1alpha levels. This compound is particularly valuable for research on clear cell renal cell carcinoma (ccRCC) [1].
Molecular Weight:
368.35
Formula:
C17H16N6O4
Target:
Others|||HIF/HIF Prolyl-Hydroxylase
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