NHE3-IN-3 (Compound 1) is a potent inhibitor of isoform 3 of the Na+/H+ exchanger (NHE3), exhibiting pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively, and demonstrates exceptional oral bioavailability of 98% in Sprague-Dawley rats [1].
Molecular Weight:
371.28
CAS Number:
[543734-50-5]
Formula:
C16H16Cl2N2O2S
Target:
Sodium Channel|||Others
T61480
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