TP0480066, a selective topoisomerase II inhibitor, demonstrates excellent inhibitory activity against DNA gyrase (IC50 = 1.10 nM) and topo IV (IC50 = 62.89 nM). This compound exhibits potent efficacy against multiple bacterial species, including drug-resistant strains. Moreover, TP0480066 displays significant inhibitory activity against N. gonorrhoeae, making it suitable for research on gonorrhea [1] [2].
Molecular Weight:
371.32
CAS Number:
[2245693-15-4]
Formula:
C18H14FN3O5
Target:
Topoisomerase|||Antibacterial|||Others
T61481
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