Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 µM. It also inhibits Mtb H37Rv with a MIC value of 0.78 µM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 µg/mL [1].
Molecular Weight:
377.4
CAS Number:
[2413974-52-2]
Formula:
C14H11N5O4S2
Target:
Others|||Antibacterial
T61570
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