COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent dual inhibitor of COX-2 and 5-LOX, exhibiting superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. It demonstrates strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 µM, 0.4 µM, and 4.96 µM, respectively [1].
Molecular Weight:
383.83
CAS Number:
[2410384-50-6]
Formula:
C14H10ClN3O4S2
Target:
Others|||COX
T61674
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