PARP1-IN-10 (compound 12c) is a highly potent and non-cytotoxic PARP1 inhibitor with an in vitro IC50 value of 50.62 nM, effectively inducing cell cycle arrest at the G2/M phase and apoptosis, while significantly augmenting the cytotoxic effects of temozolomide (TMZ) [1].
Molecular Weight:
385.41
CAS Number:
[2494001-21-5]
Formula:
C20H23N3O5
Target:
Apoptosis|||PARP|||Others
T61694
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