Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]
Molecular Weight:
385.45
Purity:
>99.99%
CAS Number:
[2489404-97-7]
Formula:
C17H24FN3O4S
Target:
STAT|||JAK|||Phosphatase
T61699
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