AMS-17 is a potent NLRP3 inhibitor that effectively suppresses microglia activation both in vitro and in vivo. Moreover, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-alpha, IL-1beta, and inducible nitric oxide synthase (iNOS), in N9 cells, making it a promising tool for investigating inflammation-associated neurological disorders [1].
Molecular Weight:
386.35
CAS Number:
[3019885-78-7]
Formula:
C15H13F3N4O3S
Target:
Others|||NOD-like Receptor (NLR)
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