COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), binding strongly at the active site of the COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory activity, COX-2-IN-14 effectively reduces ear edema and myeloperoxidase (MPO) activity in mice [1].
Molecular Weight:
386.364
CAS Number:
[2428387-48-6]
Formula:
C18H18N4O6
Target:
COX|||Others
T61711
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