TMX-4116 is a casein kinase 1alpha (CK1alpha) degrader that preferentially targets CK1alpha for degradation in cell lines including MOLT4, Jurkat, and MM.1S. TMX-4116 exhibits potent activity with degradation concentration 50 values (DC50s) below 200 nM. TMX-4116 is employed in the study of multiple myeloma and protein degradation strategies.
Molecular Weight:
389.43
CAS Number:
[2766385-56-0]
Formula:
C17H19N5O4S
Target:
Molecular Glues|||PROTACs|||Casein Kinase
T61754
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