APN/AKT-IN-1 is a potent dual inhibitor of aminopeptidase N (APN) and protein kinase B (AKT), with IC50 values of 0.21 µM for APN and 0.27 µM for AKT inhibition. The compound effectively suppresses the phosphorylation of glycogen synthase kinase 3 beta (GSK3beta), an intracellular substrate of AKT [1].
Molecular Weight:
389.45
Formula:
C18H27N7O3
Target:
Others|||Akt
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