Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 µg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria. Importantly, Antimicrobial Agent-1 exhibits no cytotoxic effects on mammalian cell lines. Its MIC values on Caco-2 and Vero cell lines are greater than 128 µg/mL [1].
Molecular Weight:
391.49
CAS Number:
[2579696-45-8]
Formula:
C22H21N3O2S
Target:
Others|||Antibacterial
T61783
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