MtTMPK-IN-1 (compound 3) is a highly effective inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), with an IC50 value of 2.5 µM. It shows moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5, making it a valuable tool for tuberculosis research [1].
Molecular Weight:
392.45
Formula:
C22H24N4O3
Target:
Antibacterial|||DNA/RNA Synthesis|||Others
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