ATR-IN-14 (compound 1) is a powerful ATR kinase inhibitor that significantly inhibits ATR signaling pathways following CHKI protein phosphorylation, with a remarkable inhibition rate of 98.03% at 25 nM. ATR-IN-14 also exhibits notable anticancer efficacy in LoVo cells, displaying an IC50 value of 64 nM [1].
Molecular Weight:
393.42
CAS Number:
[2765785-88-2]
Formula:
C20H20FN7O
Target:
Others|||ATM/ATR
T61808
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