M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD).
Molecular Weight:
394.29
Purity:
99.73%
CAS Number:
[823830-85-9]
Formula:
C15H8F6N2O2S
Target:
HIF|||HIF/HIF Prolyl-Hydroxylase
T61822
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