Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC50 values of 4.9, 11.5, 9.4, and 3.4 µM, respectively, after 24 hours of treatment. It induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression, and also demonstrates antioxidative properties [1].
Molecular Weight:
394.33
CAS Number:
[2529657-32-5]
Formula:
C17H24F3NOSe
Target:
Apoptosis|||Bcl-2 Family|||Others|||Caspase
T61823
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