Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
Molecular Weight:
310.35
Purity:
98.01%
CAS Number:
[252916-29-3]
Formula:
C18H18N2O3
Target:
Apoptosis|||VEGFR|||FGFR|||PDGFR
T6184
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