COX-2/5-LOX-IN-2 is a benzothiophen-2-ylpyrazole carboxylic acid derivative that inhibits both COX-2 and 5-LOX. COX-2/5-LOX-IN-2 (5b) has IC50 values of 5.40, 0.01, and 1.78 µM for COX-1, COX-2, and 5-LOX, respectively, and exhibits greater analgesic and anti-inflammatory activities than Celecoxib and Indomethacin.
Molecular Weight:
399.44
CAS Number:
[2410384-59-5]
Formula:
C18H13N3O4S2
Target:
COX|||Others
T61910
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