SKLB0565 is an effective inhibitor of tubulin. SKLB0565 significantly inhibited the proliferation of colorectal cancer cells with IC50 of 0.012 - 0.081 µ M. SKLB0565 induces G2/M phase arrest and mitochondria-mediated endogenous apoptosis. SKLB0565 destroys the microtubule formation of HUVECs cells and inhibits cell migration.
Molecular Weight:
400.91
CAS Number:
[2414607-10-4]
Formula:
C20H25ClN6O
Target:
Microtubule Associated|||Others|||Apoptosis
T61942
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