BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 values of 0.01 and 0.0053 µM, respectively. It exhibits a lower Pgp efflux ratio, improved passive permeability, and decreased metabolic stability in liver microsomes.
Molecular Weight:
401.57
CAS Number:
[2671036-34-1]
Formula:
C21H31N5OS
Target:
Beta Amyloid|||Beta-Secretase|||Others
T61956
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