BNS-22 is a DNA topoisomerase II (Topo II) inhibitor with IC50 values of 2.8 µM and 0.42 µM for human TopoIIalpha and TopoIIbeta-mediated kinetoplast DNA decatenation, respectively. BNS-22 induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.
Molecular Weight:
407.46
Purity:
99.62%
CAS Number:
[1151668-24-4]
Formula:
C24H25NO5
Target:
Topoisomerase
T62037
T62037
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