Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent antitumor effects with an IC50: 1.00 nM in biochemical assays.RP-3500 is 30-fold more selective for ATR than mTOR (IC50: 120 nM) and more than 2,000-fold more potent than ATM, DNA-PK and PI3Kalpha kinases. RP-3500 is 30 times more selective for ATR than mTOR (IC50: 120 nM), and 2,000 times more selective than ATM, DNA-PK and PI3Kalpha kinases.
Molecular Weight:
410.47
Purity:
99.93%
CAS Number:
[2417489-10-0]
Formula:
C21H26N6O3
Target:
ATM/ATR|||mTOR
T62083
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