Topoisomerase IIalpha-IN-2 (compound 5) is a potent inhibitor of the topoisomerase TopoIIalpha and a DNA-binding ligand. It exhibits high anti-proliferative activity in human cancer cell lines, arrests the cell cycle in the G2/M phase, and significantly induces DNA damage.
Molecular Weight:
420.42
CAS Number:
[2407521-90-6]
Formula:
C22H20N4O5
Target:
Topoisomerase|||Others
T62224
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