Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2, with IC50 values of 1.81 µg/mL for SIRT1, 2.10 µg/mL for SIRT2, and 20.5 µg/mL for SIRT3, and exhibits alpha-microtubulin hyperacetylation activity, demonstrating significant anticancer effects.
Molecular Weight:
420.93
CAS Number:
[2402779-21-7]
Formula:
C22H13ClN2OS2
Target:
Others|||Sirtuin|||Microtubule Associated
T62240
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