FLT3-IN-11 (compound 30) is an orally active, potent, and selective inhibitor of FLT3 kinase that targets wild-type FLT3 (IC50: 7.22 nM) and FLT3-D835Y (IC50: 4.95 nM), demonstrating significant anti-AML effects with an IC50 value of 3.2 nM for MV4-11 cells.
Molecular Weight:
422.45
CAS Number:
[2499966-50-4]
Formula:
C20H25F3N6O
Target:
Others|||FLT
T62260
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