Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death.
Molecular Weight:
586.68
Purity:
>99.99%
CAS Number:
[97682-44-5]
Formula:
C33H38N4O6
Target:
Autophagy|||Topoisomerase
T6228
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