PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against the human lung adenocarcinoma epithelial cell line A549 in cellular assays.PARP-1-IN-2 induced apoptosis in A549 cells.
Molecular Weight:
424.28
Purity:
99.32%
CAS Number:
[684234-55-7]
Formula:
C22H15Cl2N3O2
Target:
Apoptosis|||Caspase|||PARP
T62281
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