J-1063 is a selective, orally active and potent inhibitor of ALK5 (IC50: 0.039 µM). J-1063 inhibits inflammatory infiltration, collagen deposition, hepatocyte necrosis and exhibits anti-fibrotic effects. j-1063 has potential for liver fibrosis studies.
Molecular Weight:
425.51
CAS Number:
[2374772-46-8]
Formula:
C24H19N5OS
Target:
Others|||TGF-beta/Smad
T62301
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