PDE4B/7A-IN-1, CAS [[2511632-25-8]]
Catalog Number:
TGM-T62303
| Article Name: |
PDE4B/7A-IN-1, CAS [[2511632-25-8]] |
| Biozol Catalog Number: |
TGM-T62303 |
| Supplier Catalog Number: |
T62303 |
| Alternative Catalog Number: |
TGM-T62303-25MG,TGM-T62303-50MG,TGM-T62303-100MG |
| Manufacturer: |
TargetMol |
| Category: |
Biochemikalien |
| Compound 22, a 5-hydroxynitrile rubber 7 receptor antagonist (5-HT1A Ki=8 nm, Kb=0.04 nm, 5-nitrile rubber 7K I=451 nm, Kb=460 nm), exhibits inhibitory activity against PDE4B/PDE7A (PDE4B IC50=80.4 µM, PDE7A IC50=151.3 µM). It demonstrates significant passive biofilm penetration capabilities and high metabolic stability in vitro. Pharmacological assessment has revealed precognitive and antidepressant effects in rat behavioral tests, highlighting its potential therapeutic applications. |
| Molecular Weight: |
425.56 |
| CAS Number: |
[2511632-25-8] |
| Formula: |
C25H35N3O3 |
| Target: |
5-HT Receptor|||Others|||PDE |
![]()
|
T62303 |
