RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 µM). It blocks Hh signaling in Shh-overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe for studying Hhat catalytic function.
Molecular Weight:
430.43
CAS Number:
[2320262-09-5]
Formula:
C20H29Cl2N3OS
Target:
Others|||Hedgehog/Smoothened
T62388
* VAT and and shipping costs not included. Errors and price changes excepted