GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM [human alpha1beta2gamma2GABAA-expressing tsA201 cells] and a Ki of 28 nM [rat GABAA receptor]. GABAA receptor agent 2 TFA has no effect on four human GABA transport proteins [hGAT-1, hBGT-1, hGAT-2, and hGAT-3].
Molecular Weight:
433.42
CAS Number:
[1781880-44-1]
Formula:
C22H22F3N3O3
Target:
GABA Receptor|||Others
T62426
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