KPH2f, a dual URAT1/GLUT9 inhibitor, demonstrates safety, oral activity, and efficacy, with inhibitory concentrations (IC50s) of 0.24 µM for URAT1 and 9.37 µM for GLUT9. It exhibits minimal effects on OAT1 and ABCG2, with IC50 values of 32.14 µM and 26.74 µM, respectively [1].
Molecular Weight:
433.46
CAS Number:
[2760615-09-4]
Formula:
C24H16N3NaO2S
Target:
OAT|||Others|||transporter
T62432
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