Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
Molecular Weight:
520.89
Purity:
98.87%
CAS Number:
[1146699-66-2]
Formula:
C20H17ClF4N4O4S
Target:
Gamma-secretase
T6249
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