TRK-IN-12, CAS [[2823342-34-1]]

Product Overview

• Article Name: TRK-IN-12, CAS [[2823342-34-1]]
• Biozol Catalog Number: TGM-T62531
• Supplier Catalog Number: T62531
• Alternative Catalog Number: TGM-T62531-25MG,TGM-T62531-50MG,TGM-T62531-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

TRK-IN-12 (Compound 9e), a macrocyclic derivative, is a potent TRK inhibitor, with efficacy against TRK G595R (IC 50 = 13.1 nM). It demonstrates significant antiproliferative activity in the Ba/F3-LMNA-NTRK1 cell line (IC 50 = 0.080 µM) and exhibits superior inhibitory performance (IC 50 = 0.646 µM) compared to the control agent LOXO-101 in the Ba/F3-LMNA-NTRK1-G595R cell line [1].

Product Properties

• Molecular Weight: 439.89
• CAS Number: [2823342-34-1]
• Formula: C18H19ClFN5O3S
• Target: Others|||Trk receptor

Images

T62531