JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.
Molecular Weight:
440.49
CAS Number:
[1119503-63-7]
Formula:
C26H24N4O3
Target:
Others|||Potassium Channel|||TRP/TRPV Channel
T62543
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