TGFbetaRI-IN-4 is a potent, orally active TGFbeta receptor type I kinase (TGFbetaRI) inhibitor that targets ALK5 (IC50: 44 nM) and NIH3T3 (IC50: 42.5 nM), inhibiting tumor growth and weight in a xenograft tumor model.
Molecular Weight:
441.47
CAS Number:
[2421135-03-5]
Formula:
C23H25F2N5O2
Target:
TGF-beta/Smad|||Others
T62559
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