AMG-8718 is a selective, orally active and potent BACE1 inhibitor that acts on both BACE1 (IC50: 0.0007 µM) and BACE2 (IC50: 0.005 µM). AMG-8718 significantly reduces CSF and Abeta40 levels in the brain.
Molecular Weight:
442.44
CAS Number:
[1215868-94-2]
Formula:
C25H19FN4O3
Target:
Beta-Secretase|||Others
T62573
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