MK-2206 is an orally active, highly selective, metabotropic Akt inhibitor that targets Akt1 [IC50: 8 nM], Akt2 [IC50: 12 nM], and Akt3 [IC50: 65 nM]. Many breast cancer cell lines, PIK3CA mutants, and PTEN-losing cell lines are sensitive to MK-2206, which exhibits anti-cancer effects.
Molecular Weight:
443.94
CAS Number:
[1032349-77-1]
Formula:
C25H22ClN5O
Target:
Akt|||Others|||Apoptosis|||Autophagy
T62609
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