(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor (IC50: 3 nM) and has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells. Additionally, (R)-MLT-985 inhibits the growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.
Molecular Weight:
448.27
CAS Number:
[1832577-07-7]
Formula:
C17H15Cl2N9O2
Target:
MALT|||Others
T62680
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