Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds beta-tubulin (Kd: 0.4 µM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 µM), and also disrupts tumor vasculature.
Molecular Weight:
440.29
Purity:
99.96%
CAS Number:
[168555-66-6]
Formula:
C18H19O8P2Na
Target:
Apoptosis|||Microtubule Associated
T6272
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