AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5'-phosphatase 1). AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory effects on lymphoma growth.
Molecular Weight:
450.57
CAS Number:
[1619983-52-6]
Formula:
C27H34N2O4
Target:
Others|||Apoptosis|||Phosphatase
T62724
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