TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA), inhibiting the DNA binding activity of XPA. It acts on single, double, and cisplatin-damaged DNA with IC50 values of 18, 20, and 29 µM in fluorescence polarization (FP) assays and 21, 39, and 28 µM in ELISA assays.
Molecular Weight:
450.83
CAS Number:
[292065-64-6]
Formula:
C23H15ClN2O6
Target:
Others|||DNA/RNA Synthesis
T62730
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