AChE-IN-10 (Compound 24r) is a potent inhibitor of AChE with an IC50 value of 2.4 nM. It decreases amyloid aggregation in the presence of AChE, reduces tau phosphorylation of S396 residues, rescues neuronal morphology, and increases cell viability, thereby providing neuroprotection.
Molecular Weight:
451.53
Formula:
C23H27F2NO4S
Target:
Cholinesterase (ChE)|||Others
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